Adhatoda vasica nees acanthaceace is a well known medicinal plant from which certain alkaloids, phenolics, flavonoids, sterols and their glycoside derivatives have been isolated. Phytochemical analysis, antimicrobial efficacy and determination of bioactive components from leaves of justicia adhatoda linn g. Pharmacognosy adhatoda vasica belongs to family acanthacrae. A study on antipyretic activity of adhatoda vasica nees leaves methanolic extract. Adhatoda vasica, antispasmodic, branchodilator, anti. The present investigation was carried out to study the antiulcer activity of adhatoda vasica leaves using two ulcer models 1 ethanolinduced, and 2 pylorus. Development and evaluation of enteric coated herbal drug. Pdf secondary metabolites obtained from traditional medicinal plants. Extracts of the leaves of av are extensively used in cough, asthma, bronchitis, tuberculosis, inflammation and allergy. Malabar nut, adulsa, arusha, vasaka, justicia adhatoda, adulsa arusa, adathodai, bakash, adathoda, adalodakam, adusoge, addasaramu, lions muzzle, stallions tooth.
Justicia adhatoda, commonly known in english as malabar nut, adulsa, adhatoda, vasa, or vasaka, is a medicinal plant native to asia, widely used in siddha medicine, ayurvedic and unani systems. Chloroform extract of leaves of adhatoda vasica nees shows the presence of steroid, saponin, coumarins, alkaloids, diterpenes, phenol. Just i said its a conserved name and type is adhatoda vasica nees, which later also called as. Share your knowledge share your word file share your pdf file. Click on a scientific name below to expand it in the plants classification report. Effect of adhatoda vasica leaf powder as herbal feed. Botanical name of adhatoda family of adhatoda description of adhatoda distribution of adhatoda uses of adhatoda average dose of adhatoda advertisements. The plant has been recommended by ayurvedic physicians for the management of various types of respiratory disorders. A study on antipyretic activity of adhatoda vasica nees. The leaves of adhatoda vasica are lightgreen in colour, characteristic odour, taste is bitter, size is 10 cm long. Vasicine, isolated from the shrub adhatoda vasica, is a wellknown pyrroloquinazoline alkaloidal compound which has been used for the treatment of various diseases and disorders, mostly for the respiratorytract ailments. Links bhattacharyya d, pandit s, jana u, sen s, sur tk 2005. Quantitative determination of vasicine and vasicinone in. Issn medicinal uses and pharmacological activity of adhatoda.
Pdf therapeutic use of adhatoda vasica researchgate. Final list of references supporting the assessment of adhatoda vasica nees, folium first version pdf 92. Leaves are of dark green colour above and pale yellow below. To counter the present low content in leaves and uneconomical chemical synthesis, alternate ways to produce vasicine have been required. Adhatoda vasica nees pennel a perennial undershrub with white inflorescence found growing wild in subhimalayan tract and other regions of the country. The plant has been recommended by ayurvedic physicians for the management of various types of. The drug contains leaf, stem, flower, fruit and seeds. Paprsb institute of health sciences, university brunei darussalam. Review paper a phytopharmacological overview on adhatoda. Phytochemical and pharmacological investigations on. The present investigation was carried out to study the antiulcer activity of adhatoda vasica leaves using two ulcer models 1 ethanolinduced, and 2 pylorus ligation plus aspirininduced models. Chemical constituents and biological activities of species. Pharmacognostic study of adhatoda vasica nees bioscience. Antioxidant and antimicrobial properties of adhatoda vasica l.
The medicinal properties of adhatoda vasica nees natural order. Adhatoda vasica, also known as malabar nut tree is part of the acanthaceae plant family. Structure of major chemical constituents of adhatoda vasica nees. The standards derived from the pharmacognostical, physic chemical, phytochemical and tlchptlc studies of theseeds of adhatoda vasica neeswill be beneficial in framing the monograph of the drug in the indian pharmacopoeia. Adhatodae vasicae folium european medicines agency. Medicinal uses and pharmacological activity of adhatoda vasica and ashoke k. Medicinal uses and pharmacological activity of adhatoda vasica.
Estimations of total flavonoid content in propolis by two complementary colorimetric methods. One middle big vascular bundle and three smaller vascular bundles present in the mid rib zone. Dec 27, 2011 vasicine, isolated from the shrub adhatoda vasica, is a wellknown pyrroloquinazoline alkaloidal compound which has been used for the treatment of various diseases and disorders, mostly for the respiratorytract ailments. Development and evaluation of enteric coated herbal 35 purpose 12. In the present study medicinal uses, phytochemical analysis and pharmacognosy of plant have been revived. The fruit which holds the most potentialof the herb is a small capsule with four seeds. Ethnomedicinal value and pharmacognosy of the member of. Introduction adhatoda vasica is used as medicine in the treatment of various diseases because it has ability. It is the main ingredient in every proprietary ayurvedic medicines used for a cough and asthma. Adhatoda vasica nees on their antiinflammatory activity phytother res 2001.
Justicia adhatoda, adhatoda vasica other common names. Enhanced production of vasicine in adhatoda vasica l. The leaves are 1016cm long and greenish brown when dried and bitter in taste. Prevention of carbon tetrachloride induced hepatotoxicity. Hepatoprotective activity of adhatoda vasica aqueous leaf extract on. Due to its antiimplantation activity, adhatoda should not be used while pregnant 5. Acanthaceae, called vasa or vasaka in sanskrit, have been known in india and several other countries for thousands of years. Call for scientific data for use in hmpc assessment work on adhatoda vasica nees, folium first version pdf 66. Medicinal plant adhatoda vasica benefits and images.
Department of pharmacognosy and phytochemistry, faculty of pharmacy. Nees is a wellknown plant drug in ayurvedic and unani medicine. Adhatoda vasica plant shows various pharmacological activity like antispasmodic, fever reducer, anti. Traditional uses of adhatoda vasica nees entry parts uses country ref.
Pdf the nature has provided a complete storehouse of remedies to cure ailments of mankind. The leaves are simple, opposite, 719 cm long and 47 cm wide. In recent years the interest in this plant has increased considerably with. No reports are available for the pharmacognostical study of the seed, hence the present. Pharmacognostical and phytochemical evaluation of adhatoda. Activity of bromhexine and ambroxol, semisynthetic derivatives of vasicine from indian shrub adhatoda vasica nees. It is also available in capsule dosage form for polyherbal formulation. A phytopharmacological overview on adhatoda zeylanica. A new method of capillary electrophoresis was developed for the quantitative determination of vasicine and vasicinone from adhatoda vasica l.
Validation of different methods of preparation of adhatoda. Habitat the plant is distributed in lower himalayan range. Prevention of carbon tetrachlorideinduced hepatotoxicity in rats by adhatoda vasica leaves sir, the plant adhatoda vasica nees av of the acanthaceae family has been used for thousands of years in india. Page 176 screening of total phenolic and flavonoid content in conventional and nonconventional species of curcuma rajeshwari sahu1 and jyoti saxena1 1. A phytopharmacological overview on adhatoda zeylanica medic. The shape of leaves is ovatelanceolate, apex is acuminate, margin slightly crenate to entire, base is symmetric, venation is pinnate and texture is leathery as shown in fig. It is a simple, easily available and safe herb, which gives relief from bacterial infections and throat problems. The plant grows throughout the indian peninsula up to an altitude of 0 m. Nees sayeed ahmad, madhukar garg, maksood ali, mhaveer singh, md tanwir athar and shahid husain ansari department of pharmacognosy and phytochemistry, faculty of pharmacy jamia hamdard, hamdard nagar, new delhi 110 062, india correspondent author, email. Sampath kumar 1, debjit bhowmik 2, chiranjib 2, pankaj tiwari 2, rakesh kharel 2 1dept.
Antioxidant are nutraceuticals whose deficiency states are associated with variety of dreaded. Acanthaceae, a subherbaceous bush, found throughout the year in plains and subhimalayan tracts in india 11. A medicinal plant sunita maurya 1 and dhananjay singh 2 1faculty of pharmacy, integral university, lucknow, india 2department of chemical engineering, i. Ghosh the present survey of this plant reveals that adhatoda vasica nees belonging to family acanthaceae, commonly known as adosa, is found many regions of india and throughout the world, with a.
Adhatoda vasica nees, pharmacognostic studies, phytochemicals, adulteration and powder analysis. Materials and methods plant material plants of adhatoda vasica nees were collected from the campus of tezpur university, assam, india. Adhatoda vasica plant has a vital medicinal role in our country india as well as other country. Dual inhibitory activities of adhatoda vasica against cyclooxygenase and lipoxygenase sagheer ahmed1, saima gul2, humera gul3, muhammad hanif bangash4 1. Pharmacognostic study and phytochemical screening of leaf of. It has been used for the treatment of various diseases, particularly for the treatment of inflammatory and cardiovascular diseases. Adhatoda vasica nees acanthaceae, a perennial woody shrub is an important medicinal plant widely exploited for extraction of an alkaloid, vasicine, which is used in the preparation of vasaka, a well known drug in the ayurvedic system of medicine.
Phytochemical analysis, antimicrobial efficacy and. Pdf overview of phytochemistry and pharmacology of adhatoda. Leaves and other tender parts of the plant are utilised for various ayurvedic preparations. The electrophoretic separation was performed using a 47 cm.
Phytochemical and pharmacological investigations on adhatoda. The present survey of this plant reveals that adhatoda vasica nees belonging to family acanthaceae. Issn medicinal uses and pharmacological activity of. It is a small evergreen plant with sharp, pointed and lancelike leaves. Adhatoda vasica is a drug of choice for respiratory diseases in ayurveda. Its diverse medicinal activities include cardiovascular protection, abortifacient, antitubercular, antimutagenic, antiulcer, antiasthmatic activities. Micropropagation of adhatoda vasica neesa woody medicinal.
Important chemical constituents of leaf include pyrroloquinazoline alkaloids, vasicine, vasicol. Improved method of extraction and analysis of vasicine and vasicinone, the alkaloids of adhatoda vasica nees. Comparative study on leaf extraction adulasa adhatoda vasica by using various solvents five gm of the adhatoda vasica leaf powder was macerated with 50 ml of ethanol, methanol, hexane and chloroform. Mar 25, 2017 a study on antipyretic activity of adhatoda vasica nees leaves methanolic extract. Medicinal plant adhatoda vasica malabar nut benefits. It is reported to be an expectorant 2, abortifacient 3, antimicrobial 4,5, antitussive 6 and anticancer 7.
Prevention of carbon tetrachloride induced hepatotoxicity in. Adhatoda vasica,indian medicinal plants,ayurveda, dianmedicinalplants. It has been used for the treatment of various diseases and disorders, particularly for the respiratory tract ailments. Biological sources it is obtained from the leaves of adhatoda vasica l. The drug contains stem, leaf, flower, fruit and seeds. Kdf college of pharmacy, rkdf university, bhopal, madhya pradesh. Also has antiinflammatory, analgesic, diarrhoea, dysentery.
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